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Home News News Archive 2009 Graduate Student Jason Dean engineers metabolic pathway in mice to prevent diet-induced obesity

Graduate Student Jason Dean engineers metabolic pathway in mice to prevent diet-induced obesity

Graduate Student Jason Dean engineers metabolic pathway in mice to prevent diet-induced obesity

Mice that were engineered with a fat-burning pathway borrowed from bacteria (top) remained thin compared with normal mice (bottom) when both were fed a high-fat diet. Credit: Jason Dean, Univers

Graduate Student Jason Dean in Professor James Liao’s group engineered a synthetic metabolic pathway into mice, allowing the animals to resist diet-induced obesity.

The work was published in Cell Metabolism June 3, 2009, and featured in Technology Review, Science Daily, and UCLA news release.