CBE Seminar: Samir Mitragotri

“Understanding and Overcoming Biological Barriers for Drug Delivery”

Effective delivery of drugs is a major problem in today’s healthcare. At a fundamental level, the challenge of drug delivery reflects the fact that the drug distribution in the body is limited by body’s natural metabolic processes and transport barriers. These biological barriers, while serving an important purpose of regulating body’s metabolic functions, limit the drug dose that ultimately reaches the target site. Accordingly, many drugs fail to reach their full therapeutic potential. Our research aims at developing a fundamental understanding of body’s key biological barriers such as skin, intestinal epithelium and the immune system, and utilizing this understanding to develop novel means to negotiate these barriers to deliver drugs. Our research has led to the understanding of how transport properties of biological barriers can be modulated to deliver drugs in effective ways for the treatment of diseases such as diabetes and cancer, among others. I will present an overview of the lessons learned from our exploration of these biological barriers.

Samir Mitragotri Flyer(5-31-19)

Date/Time:
Date(s) - May 31, 2019
10:00 am - 11:00 am

Location:
Boelter Hall 3400
420 Westwood Plaza Los Angeles CA 90095